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Attainment of the highest level of microbiological quality for packing, transport and storage of sterile medical devices
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This home page inaugurates a new chapter in data-supported quality assurance with
regard to terminally sterilized medical devices that implements the International
Standards applying to sterilization in transport and storage. The various
microbial challenges in transport and storage of sterile material can be
evaluated and checked at in terms of the sterility assurance level of 1 :
1,000,000 with the method described here.
Quality assurance procedures of this kind are required because the conventional
commercial packaging for sterilized medical devices has a limited barrier
efficiency to the passage of airborne microorganisms. The procedure described
here can be used to demonstrate and verify compliance with the specifications of
the European Medical Device Directive 93/42/EEC of 1993. According to this
directive sterilized medical devices should remain sterile under the conditions
of storage and transport envisaged.
An important step consists in establishing the relevant ambient conditions. On
the basis of concrete input data, the computer program presented calculates the
microbiological challenge to the packaging of sterilized medical devices
resulting from transport and storage. The packaging must show the
appropriate effectiveness of the barrier if the sterile state is to be
maintained at the high safety level. Vice versa, it can be tested and
confirmed, whether specified limit values of the microbial
challenge are not exceeded in transport and storage so
that performance characteristics of the packaging are not overtaxed and
sterility is not endangered (EN ISO 11607-1:2006;5.5.2). This method offers
the possibility to calculate the date of expiry of sterile-packed and
stored sterilized medical devices on the basis of concrete data. A
high quality level and cost effectiveness are the basis of this
performance appraisal. It also fulfills the highest requirements and expectations
of the patient with regard to the supply of sterilized medical devices.
We are offering this program to physicians and specialised staff at hospitals and
outpatient departments, the manufacturers of medical products and those
responsible for health services.